Description

This application allows to explore heterogeneous treatment effects of preventive psychological interventions for subthreshold depression. It can be used to obtain individualized meta-analytic effect estimates for specific patients or patient groups, taking into account their personal characteristics and symptom severity. It is also possible to restrict estimates to specific types of interventions, control groups or assessment points.

Estimates are calculated from a comprehensive database of individual participant data (IPD) on preventive interventions for depression that contains eligible studies published up to 2022.

This is another heading

Lorem Ipsum is simply abc dummy text of the printing and typesetting industry. Lorem Ipsum has been the industry's standard dummy text ever since the 1500s, when an unknown printer took a galley of type and scrambled it to make a type specimen book. It has survived not only five centuries, but also the leap into electronic typesetting, remaining essentially unchanged. It was popularised in the 1960s with the release of Letraset sheets containing Lorem Ipsum passages, and more recently with desktop publishing software like Aldus PageMaker including versions of Lorem Ipsum.

Lorem Ipsum is simply dummy text of the printing and typesetting industry. Lorem Ipsum has been the industry's standard dummy text ever since the 1500s, when an unknown printer took a galley of type and scrambled it to make a type specimen book. It has survived not only five centuries, but also the leap into electronic typesetting, remaining essentially unchanged. It was popularised in the 1960s with the release of Letraset sheets containing Lorem Ipsum passages, and more recently with desktop publishing software like Aldus PageMaker including versions of Lorem Ipsum.

Technical Information

Calculations in this app are handled using shiny version 1.7.1 on an Ubuntu 22.04 x64 image with R version 4.2.2. The server on which this app is running is provided by the Metapsy collaboration on metapsy.dev.

Core functionality of the application is provided by the tlverse (version 0.0.1), metafor (version 3.9.21), metapsyTools (version 1.0.10), dmetar (version 0.1.0) and marginaleffects (version 0.11.1) packages.

The core of the codebase behind the app has been made publically available on Zenodo. Please note that we only provide the codebase of the app to display its functionality. IPD sourced by the application to generate individualized predictions is not provided due to data confidentiality but is available upon reasonable request.

© Mathias Harrer.

Go Back to Starting Page

Meta-Analytic Effect Explorer

Preventive Interventions for Subthreshold Depression

Change Analysis
Settings

Pooled Treatment Effect

  

Between-Study Heterogeneity

I2 = , τ2 = , Prediction Interval:

The pooled effect estimate is SMD=. This equals a number needed to treat of NNT = , and means that an estimated people need to receive the intervention(s) to avoid one additional case of depression. In total, individual participant data (IPD) of N= patients was used to calculate this estimate.

k= Studies available

 Individualize


  Depressive Symptoms (PHQ-9) 
  Age in Years
  Sex
  Education Level
  Employment
  Chronic Medical Condition
  Antidepressive Medication

 Study characteristics


  Intervention Type
  Control Group
  Assessment Points